Everton were among the first teams to be eliminated from the Europa League group stage after losing 3-0 to Lyon on Thursday.
Managerless Everton's recent woes continued as Cuco Martina was taken off on a stretcher with an unspecified injury minutes before half-time.
Bertrand Traore then scored on a second-half counter-attack and Houssem Aouar added a second for the French side, while Everton's hopes of a comeback ended when Morgan Schneiderlin was sent off with a second booking in the 80th minute.
Former Manchester United winger Memphis Depay added a late third from a header to complete Lyon's win.
The Premier League club have only gained a single point from the four European games -- a draw with Apollon in September.
Lyon moved onto eight points, level with Group E leaders Atalanta, who were pegged back late in a 1-1 draw as Apollon's Emilio Zelaya equalised in the 94th minute.
In Group D, AC Milan were made to wait for confirmed qualification from the group stage after being held to a 0-0 draw in a mediocre game at AEK Athens.
Home defender Helder Lopes ventured forward to fire in the first meaningful strike of the game after 14 minutes, but Gianluigi Donnarumma made the save.
It took Milan 44 minutes to muster their first shot on goal of the game as Bonucci fired a wayward effort high and wide, and with almost an hour played they came within a whisker of opening the scoring as Montolivo thumped a fierce effort against the post.
Milan still top the group on eight points, two ahead of their opponents and four clear of Austria Vienna, who cruised to a 4-1 win away to Rijeka.
Two goals from Dominik Prokop sandwiched a Domagoj Pavicic effort for the hosts before Rijeka had Josip Misic sent off with 18 minutes remaining. Further goals from Tarkan Serbest and Christoph Monschein sealed the Austrians' win.
Dynamo Kiev made it through to the knockout stage by defeating Young Boys 1-0 in Group B.
Vitaliy Buyalskiy's 70th-minute goal in Bern kept Dynamo atop Group B, two points above Partizan Belgrade, who are second after beating Skenderbeu 2-0 with goals from Zoran Tosic and Leandre Kana.
Villarreal stayed top of Group A with a 2-0 win at Slavia Prague, Carlos Bacca hitting an early opener and Simon Deli scoring an own goal two minutes from time.
Astana moved above Slavia into the second qualifying slot with a 1-0 win at Maccabi Tel Aviv, who were eliminated after Patrick Twumasi scoredthe only goal on 57 minutes.
There was no change in Group C as leaders Ludogorets were held to a 1-1 draw by second-placed Braga, Marcelinho's opener cancelled out by another Brazilian, Fransergio, for Braga seven minutes from time.
Third-placed Hoffenheim failed to capitalise as Edin Visca hit an injury time equaliser for hosts Istanbul Basaksehir, after Florian Grillitsch's early second half strike had put the hosts in command.
Lokomotiv Moscow crashed from first to third in Group F after a shock 2-1 home defeat to Sheriff. The hosts led through Jefferson Farfan but Ziguy Badibanga and Josip Brezovec replied for the visitors.
FC Copenhagen joined Sheriff on top of the group after a 3-0 win over Zlin with goals from Michael Luftner and a brace from Benjamin Verbic.
More to follow...
Source: espn.co.uk